Actually this and constipation are the only proven undesirable side effect of the long term use of opioids. They are among the safest drugs ever discovered/developed by man. They make aspirin look like cyanide by comparison. Unfortunately drug dependency of course leads to many other more unfortunate side effects. But we need to be clear when talking about opioids that they are very safe (arguably the safest drug man has yet found) and extremely effective (also arguably one of the most effective).

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Research scientist (Ph.D. micro/mol biology), Thought middle manager, Everyday junglist, Selecta (Ret.), Boulderer, Cat lover, Fish hater

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