For the even vaster majority of genes (possibly all or >99.999%) the effect of any one mutation will be impossible to predict unless the impact of all the lifestyle choices of the given individual were completely known and understood. In addition the amount of, impact, and effect of every single environmental exposure the individual had ever experienced would need to be completely known and understood. This is impossible and is the main reason why genetic testing will always remain at best a complement to more traditional routes of disease diagnosis and management. The persons who are benefiting and will benefit the most from genetic testing are not the patients in need, but the companies making, selling, and most importantly hyping these technologies way beyond what their actual importance and impact would indicate. Unfortunately a science-phobic culture is easy pickings for these hucksters. Articles like this, while purporting to help the “non scientist understand science”, do the opposite and instead spread more misinformation and confusion. Worse by giving such prominence to the topic it’s perceived importance grows even greater.
I quit nitpicking now. Sick of skimming this thing for errors and obfuscations. Too annoyed to continue.